The 2021 Ford E-Series, part of the line’s 4th generation originally launched in 2021, is a timeless and trusted choice for commercial users, dominated by cutaway models used for ambulances, delivery vans, and shuttles. It offers two engine options: a standard 7.3-liter V8 with 350 horsepower, and a more premium 7.3-liter V8 with 445 horsepower, both featuring a 6-speed automatic transmission and rear-wheel drive. These vehicles are built for heavy-duty usage and are thus not stacked with extravagant tech or luxury features. They do, however, include a basic infotainment system, air conditioning, and an optional backup camera. Notable changes for 2021 include a stronger frame and suspension components for higher payload capacity.