The 2022 Mercedes-Benz GLS is a luxurious, third generation, full-size SUV that sits at the top of the automaker's SUV lineup. It comes in three trims: the GLS 450, the GLS 580, and the AMG GLS 63, each offering an increasing level of power and luxury. The GLS 450 and GLS 580 are powered by distinctive, mild-hybrid assisted powertrains; a 362-horsepower turbocharged inline-six and a 483-horsepower V8, respectively. The high-performance AMG GLS 63 trim offers an extensive 603 horsepower from a twin-turbo V8. All engines are mated with a 9-speed automatic transmission, and 4MATIC all-wheel drive is standard across the lineup. Key safety features include automatic emergency braking, adaptive cruise control and lane keeping assist. This model features Mercedes's latest MBUX infotainment system, including a 12.3-inch digital instrument cluster and a 12.3-inch touchscreen with Apple CarPlay and Android Auto. Notable changes for the 2022 model year include a standard surround-view camera system, more color choices, and increased standard equipment such as ventilated front seats and a Burmester audio system.