2006 Mercedes-Benz CLS CLS 500

The 2006 Mercedes-Benz CLS500 is widely praised for its sleek, coupe-inspired design, smooth V8 performance, and surprisingly agile handling for a luxury sedan. As an all-new model for 2006, the CLS500 introduced Mercedes’ now-iconic “four-door coupe” styling, combining dramatic body lines with classic Mercedes elegance. Under the hood, it features a 5.0-liter V8 paired with a seven-speed automatic transmission, delivering ultra-smooth acceleration and a refined driving experience. Reviewers highlight its comfortable, quiet ride, premium interior, and Airmatic air suspension, which enhances both comfort and handling. The cabin seats four with individual seating, offering a luxurious layout, though the sloping roofline makes rear entry and headroom tighter than traditional sedansEdmunds+1. While the control interface can feel complex and fuel economy is modest, the CLS500 stands out for its distinctive styling, strong V8 power, and upscale driving feel, making it one of the most engaging Mercedes models of its era.